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Transcriptome profiling of SW480 cells and cells derived from xenograft tumors from serial transplantation of SW480 cells by RNA-sequencing

ABSTRACT: SW480 is a colorectal cancer cell line. We have shown that cancer cells are characteristic of neural stem cells and neural stemness contributes to cell tumorigenicity. We found that during serial transplantation of SW480 cells into nude mice via subcutaneous injection (in vivo passaging), the cells enhanced their neural stemness, tumorigenicity and pluripotent differentiation potential.

ORGANISM(S): Homo sapiens

PROVIDER: GSE192374 | GEO | 2022/06/30

REPOSITORIES: GEO

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