Genomics

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NGS-based miRNome reveals regulation in the miR-34/miR-449 cluster targetome in sinonasal cancers [miRNA-seq]


ABSTRACT: Using NGS-based miRNome, followed by AGO2-RIP-seq, the miR-34c and miR-449a and their direct targets were identified as factors involved in the development and progression of sinonasal cancers (SNCs). Both miR-34c and miR-449a were independent prognostic biomarkers and were associated with patient outcome.

ORGANISM(S): Homo sapiens

PROVIDER: GSE192595 | GEO | 2023/12/28

REPOSITORIES: GEO

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