Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-seq of WT, ELF4-/- CACO2 and Elf4fl/fl-Villin-Cre Livers Transcriptomes

ABSTRACT: This SuperSeries is composed of the SubSeries listed below.

ORGANISM(S): Mus musculus Homo sapiens

PROVIDER: GSE192924 | GEO | 2022/05/18

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

RNA-seq of WT, ELF4-/- CACO2 and Elf4fl/fl-Villin-Cre Livers Transcriptomes

Project description:RNA-seq of WT, ELF4-/- CACO2 and Elf4fl/fl-Villin-Cre Livers Transcriptomes

| PRJNA793825 | ENA

Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and Elf4fl/fl-Villin-Cre Livers Transcriptomes

Project description:Conclusion: Elf4fl/fl-Villin-Cre mice are more sensitive to alcohol induced liver steatosis

2022-05-18 | GSE192923 | GEO

Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and Elf4fl/fl-Villin-Cre distal colon Transcriptomes

Project description:Conclusion: Elf4fl/fl-Villin-Cre mice are more sensitive to Dextran sulfate (DSS) induced colon tumorigenesis

2021-01-07 | GSE164355 | GEO

Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and Elf4fl/fl-Villin-Cre Livers Transcriptomes

Project description:Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and Elf4fl/fl-Villin-Cre Livers Transcriptomes

| PRJNA793829 | ENA

RNA-Seq to profile transcriptomes in colonic macrophages from Tle3KO (Tle3fl/fl, Lyz2-Cre), Tle4KO (Tle4fl/fl, Lyz2-Cre) and WT (Lyz2-Cre) mice

Project description:We identified TLE3- and TLE4-regulated transcriptomes in colonic macrophages.

2023-04-07 | GSE183232 | GEO

Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and ELF4-/- CACO2 cells Transcriptomes

Project description:Conclusion: RNA sequencing of Wild Type and ELF4-/- CACO2 cells.

2022-05-18 | GSE192922 | GEO

RNA-seq Analysis of Msx2fl/fl(Msx2 WT) and Le-Cre+/- Msx2fl/fl(Msx2 CKO) Lens Transcriptomes

Project description:Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goals of this study are to compare NGS-derived lens transcriptome profiling (RNA-seq) to microarray and quantitative reverse transcription polymerase chain reaction (qRT–PCR) methods and to evaluate protocols for optimal high-throughput data analysis Methods: Lens RNA was extracted from Msx2 WT and Msx2 CKO mice at postnatal day 60 (P60) using RNAeasy™ Animal RNA Isolation Kit. The freshly frozen RNA solution was prepared for RNA sequencing on the same day. The RNA-seq was carried out using Illumina HiSeq sequencing (Novogene Bioinformatics Institute, Beijing, China). The insert size of the library was tested by Agilent 2100 Bioanalyzer to ensure library quality before Illumina HiSeq sequencing. The company used STAR software to compare RNA-seq sequencing data, HTSeq to analyze the quantitative of gene levels, RSEM to analyze transcript levels quantitatively, ClusterProfiler software to analyze differential gene enrichment, rMATS software to analyze alternative splicing, GATK software to analyze mutation sites and SnpEff software to analyze annotation of the variation sites. After mutation site detection and annotation, statistical analysis was done by Ts/Tv and Hom/Het, respectively. Results: RNA-sequencing results showed that 1,911 differentially expressed genes (DEGs) were detected. Among them, the expression of 1,586 genes were upregulated and the rest downregulated.

2018-08-24 | GSE114854 | GEO

Gene expression and ChIP profiles of Setd2 fl/fl BMSCs infected with lentivirus expressing GFP and Cre

Project description:This SuperSeries is composed of the SubSeries listed below.

2018-11-08 | GSE120361 | GEO

genes differentially expressed between the control mice (rhebFL/FL) and rheb BAD KO mice (Ucp1-cre; rhebFL/FL)

Project description:This SuperSeries is composed of the SubSeries listed below.

2021-10-21 | GSE186094 | GEO

Conventional NK cells and ILC1 are partially ablated in the livers of Ncr1 iCreTbx21 fl/fl mice.

Project description:Mouse liver contains both Eomes-dependent conventional natural killer (cNK) cells and Tbet-dependent liver-resident type I innate lymphoid cells (ILC1). In order to better understand the role of ILC1, we attempted to generate mice that would lack liver ILC1, while retaining cNK, by conditional deletion of Tbet in NKp46+ cells. Here we report that the Ncr1 iCreTbx21 fl/fl mouse has a roughly equivalent reduction in both the cNK and ILC1 compartments of the liver, limiting its utility for investigating the relative contributions of these two cell types in disease models. We also describe the phenotype of these mice with respect to NK cells, ILC1 and NKp46 + ILC3 in the spleen and small intestine lamina propria.

| S-EPMC5543419 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data