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De novo analysis of bulk RNA-seq data at spatially resolved single-cell resolution

ABSTRACT: We developed a spatially resolved RNA-seq protocol based on laser capture microdissection (LCM) and spatial barcoding strategy termed Spatial-seq. Here, we provide the demo transcriptomic data derived from mouse hypothalamus and isocortex regions for applications of our newly proposed spatial deconvolution algorithm termed Bulk2Space. We want to reveal the spatial heterogeneity and cellular diversity within the bulk brain region.

ORGANISM(S): Mus musculus

PROVIDER: GSE192999 | GEO | 2022/01/09

REPOSITORIES: GEO

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