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MCG 101 tumors implanted on prostaglandin receptor EP2 wildtype and EP2 knockout mice

ABSTRACT: Wild type tumor cells, producing high levels of prostaglandin E2 (MCG101, EP2 +/+), were inoculated on EP2 knockout (EP2 -/-) and EP2 wild type (EP2 +/+) mice. Solid tumors were dissected into tumor- and tumor-stroma tissue compartments for RNA expression microarray screening, followed by metabolic pathway analyses. The study aims to evaluate simultaneous gene pathway expressions in separate tissue compartments, such as isolated tumor tissue and tumor stroma respectively.

ORGANISM(S): Mus musculus

PROVIDER: GSE193098 | GEO | 2022/05/25

REPOSITORIES: GEO

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