Transcriptomics

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Isoform switching events in esophageal adenocarcinoma progression


ABSTRACT: Global isoform switching in esophageal adenocarcinoma (EAC) or precursor lesions has not been previously characterized. This form of alternative splicing has recently been recognized as highly prevalent in multiple other cancers. In this study, isoform switch analysis was performed using next generation sequencing of RNA isolated from patient tissues across a histopathological continuum, ranging from low risk Barrett’s esophagus (BE) to BE with advanced dysplasia. Patients were stratified based on esophageal tissue histopathology.

ORGANISM(S): Homo sapiens

PROVIDER: GSE193946 | GEO | 2022/08/17

REPOSITORIES: GEO

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