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Re-generation of cytotoxic γδT cells with distinctive signatures from human γδT-derived iPSCs

ABSTRACT: The goal of this study was to compare gene expressions on the single cell level in (i) freshly isolated PBMCs (no stimulation and no sorting), (ii) PBγδT cells; PBMCs were stimulated with HMBPP in vitro and CD3(+) γδTCR(+) cells were sorted and (iii) iγδT cells; differentiated cells from γδT-iPSC clone were stimulated with HMBPP and CD3(+) γδTCR(+) cells were sorted or not sorted.

ORGANISM(S): Homo sapiens

PROVIDER: GSE194072 | GEO | 2023/02/24

REPOSITORIES: GEO

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