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Genome-wide mapping implicates R-loops in lineage-specific processes and DNA break hotspot formation in neural stem/progenitor cells

ABSTRACT: We elucidated the genome-wide landscape of RNA:DNA hybrid structures called "R-loops" in primary neural stem/progenitor cells to assess their contribution to recurrent classes of DNA break "hotspots".

ORGANISM(S): Mus musculus

PROVIDER: GSE195963 | GEO | 2022/08/16

REPOSITORIES: GEO

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Genome-wide mapping implicates R-loops in lineage-specific processes and DNA break hotspot formation in neural stem/progenitor cells

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