Methylation profiling

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Global hypo-methylation in a subgroup of glioblastoma enriched for an astrocytic signature is associated with increased invasion and altered immune landscape. 


ABSTRACT: We describe a new molecular subgroup of glioblastoma, the most prevalent malignant adult brain tumour, harbouring a bias towards hypomethylation at defined differentially methylated regions.

ORGANISM(S): Homo sapiens

PROVIDER: GSE196339 | GEO | 2022/11/16

REPOSITORIES: GEO

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