Ribosome profiling of Murine Embryonic Fibroblasts in the context of different Fbxo4 and hnRNPK status.

ABSTRACT: Background: SCF-Fbxo4 is suspected to regulate activity of RNA binding protein hnRNPK by non-degradive ubiquitylation. Research strategy: To determine the genomic output of SCF-Fbxo4 - hnRNPK interplay, murine embryonic fibroblasts (MEFs) with different status of hnRNPK/Fbxo4 were subjected to Ribosome profiling. Sequencing was performed on total RNA and RNA protected by ribosomes for each condition.

ORGANISM(S): Mus musculus

PROVIDER: GSE196483 | GEO | 2022/09/21

REPOSITORIES: GEO