Exploring the binding motif in genome wide for p53, Pygo2 and H3K4-Me3 in mouse (Pten/Smad4 KO) PS cell line
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ABSTRACT: Since our data support that Pygo2 function is p53 Wild type status dependent and the interaction of Pygo2 with H3K4-Me3 is needed for the c-Kit regulation by Pygo2, however, neither Pygo2 nor p53 bind at c-Kit promoter region. To find out the potential co-binding locia for Pygo2, p53 and H3K4-Me3, we performed a Cut&Run assay followed by Miseq Sequencing.
ORGANISM(S): Mus musculus
PROVIDER: GSE196486 | GEO | 2022/12/23
REPOSITORIES: GEO
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