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The ATAC analysis for Usp18 heterozygous depletion in established AML1/ETO 9a leukemia mouse model

ABSTRACT: Type I IFN induces IFN stimulated genes (ISGs) and exert varieties of immunomoduratory functions. However, it is not well characterized how ISGs are regulated by negative regulators of IFN signaling. Here, we analyzed the chromatin accessibility when combined with depletion of USP18, one of major negative regulators for IFN signaling.

ORGANISM(S): Mus musculus

PROVIDER: GSE196580 | GEO | 2022/11/09

REPOSITORIES: GEO

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The transcriptomic analysis for Usp18 heterozygous depletion in established AML1/ETO 9a leukemia mouse model [AE9a_scRNA-seq]

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