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Transcriptome of epibiont Saccharibacteria TM7x during establishment of symbiosis on host Schaalia odontolyticus strain XH001

ABSTRACT: Nanosynbacter lyticus type strain TM7x was the first cultivated member of the broadly prevelent, but poorly udnerstood Candidate Phylum Radiation super-phylum. TM7x was shown to be an obligate epibiont with a host range including Schaalia odontolyticus strain XH001. The process of infecting a naive host goes through multiple phases, from an initial binding and interaction phase we call the initial encounter, to a rapid die off of infected host cells, killing phase, followed by regrowth of the host cells, regrowth phase, and finally a stable symbiosis between the species, stable symbiosis.To obtain a better understanding of the process by which these species establish a stable symbiosis, we measured the transcriptome using RNA sequencing across the course of infection. We sampled infected host, XH001/TM7x, during the initial interaction, regrowth, and after attaining stable symbiosis, as well as naive host controls grown under the same culture conditions.

ORGANISM(S): Schaalia odontolytica Candidatus Nanosynbacter lyticus

PROVIDER: GSE196744 | GEO | 2022/07/18

REPOSITORIES: GEO

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Transcriptome of epibiont Saccharibacteria TM7x during establishment of symbiosis on host Schaalia odontolyticus strain XH001

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