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Tumour-derived exosomes regulate apoptosis of CD45+EpCAM+ cells in lung cancer

ABSTRACT: Cancer-derived exosomes can deliver nucleic acids, proteins, and lipids to neighboring or distant cells and subsequently modulate recipient cells. Recently, high levels of microRNAs (miRNAs) have been identified in cancer-derived exosomes, which provide a favorable microenvironment that contribute to tumorigenesis, tumor metastasis, angiogenesis, chemoresistance, and immune escape. Howerer, the mechanism of the cancer-derived exosomes regulating CD45+EpCAM+ cell apoptosis remains unclear.

ORGANISM(S): Homo sapiens

PROVIDER: GSE197975 | GEO | 2022/05/26

REPOSITORIES: GEO

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