Transcriptomics

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Comprehensive genomic analysis of myeloid/natural killer cell precursor acute leukemia (MNKPL)


ABSTRACT: Whole exome sequencing and whole genome sequencing were performed using DNA isolated from MNKPL to identify genomic landscape. To investigate expression profiles of MNKPL, RNA sequencing (RNA-seq) was performed using RNA isolated from MNKPL. To clarify the origin and heterogeneity of MNKPL, single cell RNA-seq was conducted using leukemia cells of MNKPL and bone marrow mononuclear cells and CD34 positive bone marrow cells of a healthy donor.

ORGANISM(S): Homo sapiens

PROVIDER: GSE198016 | GEO | 2022/05/18

REPOSITORIES: GEO

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