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Transcriptome-wide profiling of RNA N4-cytidine acetylation in Arabidopsis thaliana and Oryza sativa

ABSTRACT: Using acRIP-seq, we present transcriptome-wide atlases of ac4C in Arabidopsis thaliana and Oryza sativa. Analysis of ac4C distribution reveals ac4C is enriched near translation start sites in rice while near translation start sites and end sites in Arabidopsis. Further analysis shows ac4C contributes to RNA stability, splicing and translation. We then performed NaCNBH3 treatment and RNA-seq to measure C to T mutation and RNC-seq to measure translation efficiency in Arabidopsis.

ORGANISM(S): Arabidopsis thaliana Oryza sativa

PROVIDER: GSE198286 | GEO | 2023/06/15

REPOSITORIES: GEO

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Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine

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