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An epigenetic gene signature underlies phenotype switching in early stage melanomas [YUCHIME]

ABSTRACT: A 122-epigenetic gene signature distinguished low- versus high-risk early stage melanomas. We sought to validate the signature, examined clinical correlates in a cohort of primary melanomas of the skin, and studied the underlying transcriptomic aberrations and changes in chromatin in cell lines representing these two groups.

ORGANISM(S): Homo sapiens

PROVIDER: GSE198427 | GEO | 2024/05/08

REPOSITORIES: GEO

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