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Immune transcriptome in adult-onset Still’s disease with mild flare following administration of mRNA vaccine BNT162b2

ABSTRACT: Adult-onset Still’s disease (AOSD) patients represent a population for which vaccination can induce disease flare1. The COVID-19 pandemic vaccination programs presented these patients and their health care providers with a critical decision. Previously it has been described that AOSD patients can experience disease flare with COVID-19 vaccination but no one has yet reported their immune transcriptional and antibody response. Here we present the transcriptional response and anti-spike antibody profile of a 58-year-old male after vaccination with BNT162b2 who experienced a mild AOSD flare following the second vaccine.

ORGANISM(S): Homo sapiens

PROVIDER: GSE198549 | GEO | 2022/05/18

REPOSITORIES: GEO

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