TREM2 shapes myeloid cell activations in trauma- and autoimmune-mediated neurodegeneration
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ABSTRACT: TREM2 signaling in myeloid cells functions as a major pathology-induced immune signaling hub in trauma- and autoimmune-mediated neurodegeneration. Here we compared the influence of TREM2 signaling on single-cell transcriptional profiles of mouse myeloid populations during the pathologies of spinal cord injury (SCI) and multiple sclerosis (MS) models.
ORGANISM(S): Mus musculus
PROVIDER: GSE198852 | GEO | 2023/06/06
REPOSITORIES: GEO
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