Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Analysis of red blood cells from rainbow trout Oncorhynchus mykiss infected by Tetracapsuloides bryosalmonae

ABSTRACT: The myxozoan Tetracapsuloides bryosalmonae is the causative agent of proliferative kidney disease (PKD) – a disease of salmonid fishes, notably of the commercially farmed rainbow trout Oncorhynchus mykiss. Both wild and farmed salmonids are threatened by this virulent/deadly disease, which is often expressed by swollen kidneys. In order to understand the causes and consequences of the disease, we studied the immune response towards the parasite. To profile the influence of the disease on these cells, we produced a transcriptome of teleost RBCs in health and disease. Compared to erythrocytes originating from healthy fish, PKD fundamentally altered RBCs in their metabolism, adhesion, and response to inflammation.

ORGANISM(S): Salmo salar Oncorhynchus mykiss

PROVIDER: GSE198859 | GEO | 2022/08/31

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Oncorhynchus mykiss

Project description:Rainbow trout red blood cells (RBCs): Control vs Heat shock, repeated samples from individuals

| PRJNA126725 | ENA

Oncorhynchus mykiss strain:Norwegian farmed population

Project description:Oncorhynchus mykiss strain:Norwegian farmed population Variation

| PRJNA253782 | ENA

Transcriptional changes in innate immunity genes in head kidney associated with Aeromonus salmonicida infection in polycyclic aromatic hydrocarbon mixture-fed rainbow trout

Project description:Responses of salmonid populations to ecosystem degradation often, if not typically, involve multiple stressors. The interaction of disease and contaminant exposure is of potential relevance to persistence of salmonid populations. The duration of PAH exposure and the life stage of exposure in the trout reflect a likely exposure scenario for some stocks of anadromous salmonids (sub-yearling ocean-type Chinook salmon) during emigration to the ocean. This current study focuses on the genes expressed in rainbow trout after exposure to both the high molecular weight PAH mixture and to the A. salmonicida pathogen.

2016-12-20 | GSE87920 | GEO

Oncorhynchus mykiss

Project description:Puffy Skin Disease is an emerging transmissible condition in rainbow trout Oncorhynchus mykiss Walbaum

| PRJNA321827 | ENA

Potential biomarker genes for crowding stress in rainbow trout Oncorhynchus mykiss

Project description:Stocking density is considered as a key factor determining the productivity of fish aquaculture systems. The transcriptomic response to crowding stress is, however, still poorly investigated. We aimed at the identification of potential biomarker genes via microarray analyses to get insight into molecular pathways modulated through density-induced stress in farmed rainbow trout Oncorhynchus mykiss. Transcriptome profiling in liver, kidney, and gills was complemented with behaviarol observation and analysis of classical plasma parameters. Individuals of two trout strains were exposed for eight days to definite stocking densities, 1 kg/m³ (low density); 10 kg/m³ (moderate); 18 kg/m³ (elevated); and 35 kg/m³ (high). Whereas stocking density had no significant effect on cortisol levels, plasma glucose levels were elevated in trout kept at high density. Pathway enrichment analyses confirmed the upregulation of HIF1a signaling in liver contributing to glucose homeostasis during stress conditions, while mTOR and PI3K/AKT signaling pathways were downregulated. Further perturbed hepatic pathways were involved in protein ubiquitination and the biosynthesis of cholesterol, retinol and glutathione.

2015-10-24 | GSE74332 | GEO

Oncorhynchus mykiss

Project description:Discovery of genes associated with whirling disease infection and resistance in rainbow trout using expression profiling

| PRJNA101813 | ENA

Protein metabolism drives feed efficiency in the liver and white muscle of efficient and inefficient Chinook salmon (Oncorhynchus tshawytscha) farmed in saline water

Project description:Understanding the molecular mechanisms of feed efficiency is an important step toward sustainability of salmonids aquaculture. In this study, the liver and white muscle proteomes of efficient (EFF) and inefficient (INEFF) Chinook salmon (Oncorhynchus tshawytscha) farmed in sea water were investigated by liquid chromatography-tandem mass spectrometry (LC-MS/MS) approach. In total, 2,746 liver and 702 white muscle quantified proteins were compared between 21 EFF and 22 INEFF fish. Protein synthesis was enriched in both liver and white muscle of the EFF group while conversely, pathways related to protein degradation (amino acid catabolism and proteolysis, respectively) were the most affected processes in the liver and white muscle of INEFF fish. The SOM in the INEFF group was significantly higher than EFF fish showing INEFF fish probably was the dominant group. The INEFF group (dominant) suffered stress and shifted to consume energy through protein catabolism. As the first study, the results provide a preliminary picture of the fundamental molecular landscape of feed efficiency in Chinook salmon farmed in sea water

2023-04-27 | PXD028025 | Pride

Oncorhynchus mykiss

Project description:Using RAD Tags Sequencing for Detecting and Validating QTL Affecting Bacterial Cold Water Disease Resistance in Rainbow Trout

| PRJNA275757 | ENA

Oncorhynchus mykiss

Project description:Identification of single nucleotide polymorphism markers associated with bacterial cold water disease resistance and spleen size in rainbow trout

| PRJNA292117 | ENA

Oncorhynchus mykiss

Project description:Toxicity of atrazine and nonylphenol in juvenile rainbow trout (Oncorhynchus mykiss): Effects on general health, disease susceptibility and gene expression

| PRJNA168503 | ENA

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data