Methylation profiling

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Meta-analysis of Epigenome Wide Association Studies of Major Depressive Disorder


ABSTRACT: EPIC array data were generated from 2 MDD case control cohorts. EWAS was performed in each cohort, followed by meta-analysis between the 2 cohort. Cohort 1: A total of 191 blood samples from 112 patients with MDD was collected up till the interim analysis (wave 1 samples) from an observational clinical study OBSERVEMDD0001 (ClinicalTrials.gov Identifier: NCT02489305) compared to 32 healthy controls; Cohort 2: The MDD cases (N = 359) were drawn from the Molecular Biomarkers of Antidepressant Response study compared to 68 healthy controls.

ORGANISM(S): Homo sapiens

PROVIDER: GSE198904 | GEO | 2022/11/03

REPOSITORIES: GEO

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