Transcriptional responses of Folsomia candida exposed to polar and apolar narcotizing compounds.

ABSTRACT: Narcosis or baseline toxicity is the inert toxicity of hydrophobic compounds, supposed to take place at the level of the cellular membranes. Based on the linear relationship between the toxicity (logEC50) and the hydrophobicity (logKow), class I and II narcotizing compounds are recognized, in which the latter group is assumed to exert additional toxic mechanisms by hydrogen bond donor acidity by their polar groups. Chlorinated anilines, which occur often in the environment as degradation products of certain pesticides , are considered to be narcotizing compounds. In this study the transcriptional responses of the soil arthropod Folsomia candida are investigated upon exposure to a series of anilines with increasing chlorination. A discrimination between class1 and class2 narcotizing compound is being made.

ORGANISM(S): Folsomia candida

PROVIDER: GSE19929 | GEO | 2010/02/03

SECONDARY ACCESSION(S): PRJNA122005

REPOSITORIES: GEO