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Morphine addiction-NAc_small RNA sequencing

ABSTRACT: The current study aimed at addressing two questions: 1) How the expression of key miRNAs is altered in the NAc during the morphine-induced addiction? 2) Which is/are the target gene(s) and what is/are the regulatory mechanism(s) of gene(s) in response to the candidate miRNAs? To answer these two questions, the morphine addiction model was first established by using the conditioned place preference (CPP) paradigm. Then, the aberrant expression of miRNAs was identified in the NAc tissue by RNA-sequencing.

ORGANISM(S): Mus musculus

PROVIDER: GSE199917 | GEO | 2022/04/04

REPOSITORIES: GEO

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Morphine addiction-NAc_RNA sequencing

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