Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RHAMMB promotes metastasis of pancreatic neuroendocrine tumor

ABSTRACT: Analysis of molecular mechanisms by which RHAMMB promote metastasis of pancreatic neuroendocrine tumor.

ORGANISM(S): Mus musculus

PROVIDER: GSE200497 | GEO | 2024/04/16

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

RHAMMB promotes metastasis of pancreatic neuroendocrine tumor

Project description:RHAMMB promotes metastasis of pancreatic neuroendocrine tumor

| PRJNA824826 | ENA

Pancreatic Stellate Cells Promote Growth and Metastasis of Pancreatic Neuroendocrine Tumor

Project description:Pancreatic Stellate Cells Promote Growth and Metastasis of Pancreatic Neuroendocrine Tumor

| PRJNA704287 | ENA

MicroRNA-431 promotes metastasis of pancreatic neuroendocrine tumors by targeting DAB2IP, a RasGAP tumor suppressor

Project description:Analysis of pathways regulated by miR-431 at the mRNA expression levels in pancreatic neuroendocrine tumor cells

2019-11-21 | GSE139119 | GEO

Proteogenomic characterization of pancreatic neuroendocrine tumor

Project description:To characterize pancreatic neuroendocrine tumor at protein level, we performed mass spectromery-based proteome analysis using clinical FFPE tissue samples.

2024-07-10 | PXD034571 | Pride

MicroRNA-431 promotes metastasis of pancreatic neuroendocrine tumors by targeting DAB2IP, a RasGAP tumor suppressor

Project description:MicroRNA-431 promotes metastasis of pancreatic neuroendocrine tumors by targeting DAB2IP, a RasGAP tumor suppressor

| PRJNA578481 | ENA

Single-cell RNA-sequencing of metastatic pancreatic neuroendocrine tumor

Project description:Single-cell RNA-sequencing of metastatic pancreatic neuroendocrine tumor

| PRJNA682637 | ENA

A cross species and multi-omics (including metabolomics) analysis in pancreatic neuroendocrine tumours (tumor stages)

Project description:Pancreatic neuroendocrine tumor (PanNET) is relatively infrequent but is nevertheless metastatic. Seeking to extend a new paradigm of personalized medicine, we performed an integrative analysis of transcriptomic (mRNA and microRNA) and mutational profiles and defined three clinically relevant human PanNET subtypes. Importantly, cross-species analysis revealed two of these three subtypes in a well-characterized, genetically engineered mouse model (RIP1-Tag2) of PanNET and its cell lines. Each subtype share similarities to distinct cell types in pancreatic neuroendocrine development, features are reflected in their metabolic profiles. Subtype-specific molecular signatures metabolites are proposed to identify these subtypes. Gene expression data from different stages of RIP1-TAG2 genetically engineered PanNET mouse model RT2 mouse PanNET tumors, liver metastases, normal, hyperplastic, and angiogenic islets were dissected out or isolated. RNA was extracted and hybridized on Affymetrix GeneChip Mouse Gene 1.0 ST arrays. The CEL files were processed using aroma.affymetrix.

2015-10-30 | E-GEOD-73514 | biostudies-arrayexpress

Engrailed-1 Promotes Pancreatic Cancer Metastasis

Project description:Engrailed-1 Promotes Pancreatic Cancer Metastasis

| PRJNA951660 | ENA

Affymetrix SNP 6.0 array data from neuroendocrine primary tumor and its metastasis

Project description:Reports on common mutations in neuroendocrine tumors (NET) are rare and clonality of NET metastases has not been investigated in this tumor entity yet. We selected a NET and a the corresponding lymph node and liver metastases as well as the derivative cell lines to screen for somatic mutations in the primary NET and to track the fate of genetic changes (by Affymetrix SNP 6.0 micorarray and targeted resequencing by 454 GS FLX) and during metastasis and in vitro progression. using Affymetrix SNP 6.0 Arrays. Affymetrix SNP 6.0 arrays were performed according to the manufacturer's directions on DNA extracted from cryo material or cell lines. Copy number analysis of Affymetrix SNP 6.0 arrays was performed for 4 samples. 60 samples from HapMap database were used as references for copy number inference.

2012-07-16 | E-GEOD-39371 | biostudies-arrayexpress

Transcription profiling of midgut carcinoid (neuroendocrine) primary tumors and metastasis

Project description:Gene expression profiling of midgut carcinoid (neuroendocrine) primary tumors and metastasis

2008-10-30 | E-TABM-389 | biostudies-arrayexpress