Genomics

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Target genes of thyroid hormone (TH) in brown adipose tissue (BAT) and their role during metabolic stressors [ChIP-seq]


ABSTRACT: To understand the role of TH target genes in BAT, we developped a murine transgenic model which expressed a tagged-form of the thyroid hormone receptor alpha (TRa1, tagged with GS which is a fusion between protein G and streptavidin) specifically in brown adipocytes. Combined with RNAseq data, it allowed to establish the direct target genes of thyroid hormones (TH) in brown adipocytes

ORGANISM(S): Mus musculus

PROVIDER: GSE201124 | GEO | 2022/04/29

REPOSITORIES: GEO

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