Transcriptomics

Dataset Information

0

IL-6 driven pSTAT1 response is linked to T cell features implicated in early immune dysregulation 


ABSTRACT: Here, we performed an in-depth characterization of the effect of classic IL-6 signaling in primary human T cells from healthy individuals. We generated a detailed map of IL-6 signaling in CD4+ and CD8+ naïve and memory T cell subsets, linking mbIL-6R expression levels to the magnitude and balance of phosphorylation of STAT1 and STAT3 and the transcriptomics response to IL-6 in these subsets.

ORGANISM(S): Homo sapiens

PROVIDER: GSE201180 | GEO | 2022/06/27

REPOSITORIES: GEO

Shared Molecules

Only show the datasets with similarity scores above: 0.5
     

Similar Datasets

2021-11-02 | PXD028374 | Pride
2020-10-22 | GSE159782 | GEO
| S-EPMC9327741 | biostudies-literature
2016-09-19 | GSE78922 | GEO
| PRJNA828611 | ENA
2024-08-21 | GSE265853 | GEO
2024-08-21 | GSE265855 | GEO
2014-09-09 | E-GEOD-61201 | biostudies-arrayexpress
2015-07-01 | E-GEOD-63204 | biostudies-arrayexpress
2023-12-18 | GSE241139 | GEO