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An experimental model for ovarian cancer: Propagation of ovarian cancer initiating cells and generation of ovarian cancer organoids

ABSTRACT: To establish an iOCIC model, an high-grade serous ovarian cancer (HGSOC) cell line, OVCAR-3 was reprogrammed by transducing Yamanaka four factors OCT4, SOX2, KLF4 and MYC (OSKM) We then performed gene expression profiling analysis using data obtained from RNA-seq of 3 different cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE201206 | GEO | 2022/09/20

REPOSITORIES: GEO

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