Project description:To determine differences between Idh1 mutant and control growth plates, we used scRNA sequencing. Three E18.5 growth plates from our Idh1 mutant mice and three control mice were studied. Differential gene expression analysis revealed genes that were expressed in the distinct clusters.
Project description:As another method to determine differences between Idh1 mutant and control growth plates, we used Bulk RNA sequencing. Three E18.5 growth plates from our Idh1 mutant mice and three control mice were studied. Differential gene expression analysis revealed genes that were expressed in the distinct clusters, further supporting our single cell RNA data.