Transcriptomics

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Expression data from mammary epithelia and mammary fibroblasts from mice with and without epithelial KrasG12D and with and without stromal p53 deletion


ABSTRACT: p53 is a known tumor suppressor. We have found that stromal p53 regulates breast cancer development, the immune landscape, and survival in an oncogene specific manner when comparing the epithelial oncogenes ErbB2 and KrasG12D In this dataset, we have evaluated mammary epithelia from mice with and without epithelial KrasG12D and with and without stromal p53 deletion. We have also evaluated mammary fibroblasts from mice with and without epithelial KrasG12D and with and without stromal p53 deletion.

ORGANISM(S): Mus musculus

PROVIDER: GSE201935 | GEO | 2022/05/01

REPOSITORIES: GEO

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