Transcriptomics

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Single Cell RNA-seq on Human PBMC


ABSTRACT: To assess the impact of IgG1 and IgG4 variants of a TIGIT-Fc-LIGHT fusion protein on human PBMC expression, each fusion protein or an untreated control were incubated with human PBMC for 2 days in AIMV lymphoproliferative media. Both IgG1 and IgG4 variants of TIGIT-Fc-LIGHT induced broad immune cell activation on T, NK, and myeloid cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE201999 | GEO | 2022/05/27

REPOSITORIES: GEO

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