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Gene expression profiles in ethylene glycol-induced renal stone formation and phlorizin treatment

ABSTRACT: Microarray analysis for total RNA from rat renal cortex and outer meulla. Nephrolithiasis is a disorder with a poor quality of life due to severe pain and no effective medication. Sodium-glucose cotransporter-2 (SGLT2) inhibitors, an anti-diabetic agent, have diuretic and anti-inflammatory effects, suggesting their benefit in treating nephrolithiasis. However, the effects of SGLT2 inhibition against renal stone formation have not been elucidated. To check gene expression profiles, microarray analysis was performed.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE202031 | GEO | 2023/03/22

REPOSITORIES: GEO

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