Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Golden-mantled ground squirrel (Spermophilus lateralis) hibernating liver transcriptome

ABSTRACT: This series represents the liver transcriptome for animals sampled during summer, interbout arousal, and late torpor Keywords = squirrel Keywords = liver Keywords = hibernation Keywords: other

ORGANISM(S): Callospermophilus lateralis

PROVIDER: GSE2024 | GEO | 2004/12/03

SECONDARY ACCESSION(S): PRJNA91851

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Golden-mantled ground squirrel (Spermophilus lateralis) hibernating heart transcriptome

Project description:This series represents the heart transcriptome for animals sampled during summer, interbout arousal, and late torpor Keywords = squirrel, heart, hibernation Keywords: other

2004-12-03 | GSE2023 | GEO

Golden-mantled ground squirrel (Spermophilus lateralis) hibernating liver transcriptome

Project description:This series represents the liver transcriptome for animals sampled during summer, interbout arousal, and late torpor Keywords = squirrel Keywords = liver Keywords = hibernation

2010-06-05 | E-GEOD-2024 | biostudies-arrayexpress

Golden-mantled ground squirrel (Spermophilus lateralis) hibernating heart transcriptome

Project description:This series represents the heart transcriptome for animals sampled during summer, interbout arousal, and late torpor Keywords = squirrel, heart, hibernation

2010-06-05 | E-GEOD-2023 | biostudies-arrayexpress

Golden-mantled ground squirrel (Spermophilus lateralis) hibernating brain transcriptome

Project description:This series represents the brain transcriptome for animals sampled during summer, interbout arousal, and late torpor. Note that the brain expression data for interbout aroused animals was not analyzed in our publication because the group consisted of just 2 animals. Keywords = squirrel, brain, hibernation Keywords: other

2004-12-03 | GSE2022 | GEO

Golden-mantled ground squirrel (Spermophilus lateralis) hibernating brain transcriptome

2010-06-05 | E-GEOD-2022 | biostudies-arrayexpress

13-lined ground squirrel (Spermophilus tridecemlineatus) hibernating liver transcriptome

Project description:This series represents the liver transcriptome for animals sampled during summer, interbout arousal, and late torpor Keywords = squirrel, liver, hibernation Keywords: other

2004-12-03 | GSE2021 | GEO

13-lined ground squirrel (Spermophilus tridecemlineatus) hibernating liver transcriptome

Project description:This series represents the liver transcriptome for animals sampled during summer, interbout arousal, and late torpor Keywords = squirrel, liver, hibernation

2010-06-05 | E-GEOD-2021 | biostudies-arrayexpress

StrokeofGenus: RNA-seq in five tissues of the hibernating 13-lined ground squirrel

Project description:Identify shifts in gene expression relevant to torpor phenotypes and recovery following torpor in five tissues of the 13-lined ground squirrel. Sampled tissues and time points overlap with prior hibernation RNA-seq studies in 13-lined ground squirrel and other species, allowing for the analysis of conserved gene expression patterns in torpor.

2024-10-23 | GSE248932 | GEO

Comparative transcriptomics of the garden dormouse hypothalamus during early torpor, late torpor and interbout arousal of hibernation

Project description:Comparative transcriptomics of the garden dormouse hypothalamus during early torpor, late torpor and interbout arousal of hibernation

2023-11-13 | GSE207494 | GEO

Protein expression and phosphoproteome of brown adipose tissue in the hibernating ground squirrel

Project description:Mammalian hibernation is characterized by metabolic rate depression and a strong decrease in core body temperature that together create energy savings such that most species do not have to eat over the winter months. Brown adipose tissue (BAT), a thermogenic tissue that uses uncoupled mitochondrial respiration to generate heat instead of ATP, plays a major role in rewarming from deep torpor. The present study used label-free phosphoproteomics to investigate changes in BAT from thirteen-lined ground squirrels (Ictidomys tridecemlineatus), comparing euthermic squirrels with squirrels in deep torpor. Differential expression of mitochondrial proteins was also investigated. Surprisingly, mitochondrial membrane and matrix protein expression in BAT was largely constant between active euthermic squirrels and their hibernating counterparts. Validation by immunoblotting confirmed that the protein levels of mitochondrial respiratory chain complexes were largely unchanged. However, phosphoproteomics showed that pyruvate dehydrogenase (PDH) phosphorylation increased during ground squirrel hibernation, and this was confirmed by immunoblotting with phospho-specific antibodies. PDH phosphorylation leads to its inactivation, which suggests that BAT carbohydrate oxidation is inhibited during hibernation. Phosphorylation of hormone-sensitive lipase (HSL) also increased during hibernation, suggesting that HSL would be in a partly activated state in BAT to produce the fatty acids that are likely the primary fuel for thermogenesis during arousal.

2017-07-11 | PXD004261 | Pride

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data