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Inflammation modulates intercellular adhesion and mechanotransduction in human epidermis via ROCK2

ABSTRACT: The cytoskeletal mechanisms regulating inflammatory responses in the epidermis are not well described. Here we addressed this question by inducing a psoriatic phenotype in human keratinocytes and reconstructed human epidermis using a cytokine stimulation model.We report the results from RNA-seq in N/TERT keratinocytes treated with M5 or both M5 and ROCK2 inhibitor KD025.

ORGANISM(S): Homo sapiens

PROVIDER: GSE202522 | GEO | 2022/05/13

REPOSITORIES: GEO

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Inflammation modulates intercellular adhesion and mechanotransduction in human epidermis via ROCK2

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Inflammation modulates intercellular adhesion and mechanotransduction in human epidermis via ROCK2.

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