Genomics

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Chromatin accessibility and mitochondrial genotype from single cells of the retina and choroid in human MELAS (m.3243A>G) and control samples [scATAC-seq]


ABSTRACT: The mitochondrial m.3243A>G variant is known to cause retinal dystrophy and vision loss. We used mitochondria single cell ATAC sequencing to measure nuclear chromatin accessibility and mitochondrial heteroplasmy in single cells of the retina and choroid.

ORGANISM(S): Homo sapiens

PROVIDER: GSE202746 | GEO | 2023/06/08

REPOSITORIES: GEO

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