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EZH2 KO RNA-seq in HSC-5 cells

ABSTRACT: CRISPR was used to deplete EZH2 in HSC-5 cells. RNA-seq was then carried out to identify changes in the transcriptome following EZH2 loss in these cells. Critically, we identified TP63 to be downregulated in the EZH2-depleted cells, and also RUNX3 to be significantly upregulated.

ORGANISM(S): Homo sapiens

PROVIDER: GSE202782 | GEO | 2022/06/19

REPOSITORIES: GEO

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