Transcriptomics

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Role of B cells in generating anti-melanoma immunity in response to anti-PD-L1 antibody therapy


ABSTRACT: B cells potentially play a role in the immune response to melanoma, including during treatment with immune modulators. We profiled (transcriptome analysis) effects of anti-PD-L1 antibody therapy on gene expression in B16 melanoma tumors of B cells depleted and WT syngeneic mice. After 7 days of B16 tumors implantation, mice were treated or untreated with anti-PD-L1 antibody (every three days).

ORGANISM(S): Mus

PROVIDER: GSE202879 | GEO | 2022/05/15

REPOSITORIES: GEO

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