Genomics

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ARID1A-deficient Bladder Cancer is Dependent on PI3K Signaling, and can be Targeted via EZH2 and/or PI3K Pharmacologic Inhibition: Therapeutic Implications


ABSTRACT: ARID1A-mutant bladder cancer is dependent on PI3K signaling and is sensitive to EZH2 and/or PI3K inhibition. Clinical trials in molecularly selected patients should be considered.

ORGANISM(S): Homo sapiens

PROVIDER: GSE203033 | GEO | 2022/08/22

REPOSITORIES: GEO

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