Transcriptomics

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Transcriptional profiling of melanoma-associated lymphatic endothelial cells (LECs)


ABSTRACT: Objective was to uncover the transcriptional changes occuring in melanoma-associated LECs relative to LECs of naïve skin. To investigate the transcriptional changes in LECs during tumor development, RNA was extracted from LECs sorted from naïve skin and BPC (Tyr::Cre-ER, BRafV600E) murine melanomas and bulk RNA-seq performed. Naïve skin LECs were collected from 3 mice and tumor-associated LECs collected from 4 mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE203307 | GEO | 2023/01/20

REPOSITORIES: GEO

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