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The effects of SCAP deletion on gene expression of activated B cells

ABSTRACT: To investigate the role of SREBP signaling in B cell activation, we stimulated SCAP+/+CD19Cre/+ (WT) and SCAPfl/fl CD19Cre/+ (KO) B cells with LPS, anti-CD40 or anti-IgM for 24 hrs and performed RNA sequencing to identifiy the differences.

ORGANISM(S): Mus musculus

PROVIDER: GSE204913 | GEO | 2022/06/30

REPOSITORIES: GEO

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Deletion of Scap in Alveolar Type II Cells Influences Lung Lipid Homeostasis and Identifies a Compensatory Role for Pulmonary Lipofibroblasts

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