Genomics

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Chromatin Analysis of Wilms Tumor Highlights Stem Cell Properties and a Renal Developmental Network


ABSTRACT: Wilms tumors are pediatric cancers thought to arise from kidney-specific stem cells. In order to identify transcriptional and epigenetic mechanisms that drive these malignant cells, we compared genomewide chromatin profiles of Wilms tumors to embryonic stem (ES) cells and normal kidney.

ORGANISM(S): Homo sapiens

PROVIDER: GSE20512 | GEO | 2010/05/05

SECONDARY ACCESSION(S): PRJNA125231

REPOSITORIES: GEO

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