Pro-inflammatory activity of SARS-CoV-2 viral peptide-dsRNA complex on human dermal microvascular endothelial cells (HDMVEC)
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ABSTRACT: To investigate how SARS-CoV-2 viral peptides alter the immune sensing program in HDMVEC, we treated HDMVEC with SARS-CoV-2 viral peptide-dsRNA complex (xenoAMP(S)-dsRNA), Control(S)-dsRNA, dsRNA only or their associated controls. Control(S) was the homolog sequence of xenoAMP(S) from low pathogenic human coronavirus-OC43(HCoV-OC43). The gene expression profiles in the stimulated HDMVEC were analyzed with RNA sequencing.
ORGANISM(S): Homo sapiens
PROVIDER: GSE205487 | GEO | 2023/11/01
REPOSITORIES: GEO
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