Transcriptomics

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Liver transcriptome profiling of liver specific miR-122 knockout and control male mice


ABSTRACT: Liver transcriptome profiling of liver specific miR-122 knockout (miR-122loxP/loxP Alb-Cre) and control (miR-122loxP/loxP) male mice. Expression profile of several hundred mRNAs that include miR-122 targets were altered in miR-122 KO livers. Loss of miR-122 in the germ line resulted in significant changes in hepatic gene expression profile. Among the upregulated genes many are direct targets of miR-122

ORGANISM(S): Mus musculus

PROVIDER: GSE20610 | GEO | 2012/03/03

SECONDARY ACCESSION(S): PRJNA124787

REPOSITORIES: GEO

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