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Identification of the circadian clock genes as components of the compensatory mechanism in nphp8 mutant zebrafish

ABSTRACT: The nphp8sa24730 mutant zebrafish displayed a marked decrease in glomerular cysts and cloaca malformation over subsequent generations, implying the existence and activation of compensatory mechanisms that could rescue the ciliopathy-associated phenotypes. To uncover these mechanisms, we compared the transcriptional profiles of two-day-old maternal zygotic homozygous nphp8sa24730 mutant larvae and control siblings by RNA sequencing (RNA-seq).

ORGANISM(S): Danio rerio

PROVIDER: GSE206983 | GEO | 2022/07/22

REPOSITORIES: GEO

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