Methylation profiling

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Sex-based comparison of CD4+ T cell DNA methylation patterns in SLE reveals pro-inflammatory epigenetic changes in men


ABSTRACT: Male patients with systemic lupus erythematosus (SLE) experience severe disease compared to female patients, despite the disease being more prevalent in females. For the time, we compared genome-wide differential methylation in CD4+ T cells between male (n=12) and female (n=10) SLE patients.

ORGANISM(S): Homo sapiens

PROVIDER: GSE207861 | GEO | 2023/06/07

REPOSITORIES: GEO

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