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Timing and cell specificity of senescence drives postnatal lung development and injury

ABSTRACT: Senescence causes age-related diseases and stress-related injury. Paradoxically, it is also essential for organismal development. Whether senescence contributes to lung development or injury in early life remains unclear. This work defines the ontogeny of lung senescence and provides an optimal therapeutic window for mitigating neonatal hyperoxic lung injury by clearing senescence.

ORGANISM(S): Mus musculus

PROVIDER: GSE207866 | GEO | 2022/12/05

REPOSITORIES: GEO

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