Transcriptomics

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Expression data from cultured macrophages and osteoclasts


ABSTRACT: Osteoclastogenesis is induced by the stimulation of RANKL. In the early stage of osteoclast differentiation, the osteoclast progenitor cells are primed by M-CSF, following a tightly controlled genetic program where specific sets of genes are up-regulated by RANKL. Some of them, for instance, control differentiation, cell-cell fusion and bone resorption. We used microarrays to detail the global program of gene expression underlying osteoclastogenesis and identified various up-regulated genes during this process.

ORGANISM(S): Mus musculus

PROVIDER: GSE20850 | GEO | 2010/03/22

SECONDARY ACCESSION(S): PRJNA124757

REPOSITORIES: GEO

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