Transcriptomics

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YM155 in combination with EZH2 inhibiton induces synthetic lethality


ABSTRACT: EZH2 inhibitors have been developed to treat certain cancers. To maximize the anticancer acttivity of EZH2 inhibition, we combined an EZH2 inhibitor EPZ6438 with YM155, which leads to dramatic cell death. We used microarrays to detail the global gene expression profiles.

ORGANISM(S): Homo sapiens

PROVIDER: GSE208593 | GEO | 2023/01/13

REPOSITORIES: GEO

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