Transcriptomics

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Affymetrix Mouse liver gene expression profiling of Cross B6/J x A/J


ABSTRACT: Summary Mapping the genetic architecture of RNA transcript abundances has potential for revealing molecular mechanisms underlying complex traits like disease. Gene expression microarrays allow monitoring genetic control on a whole transcriptome level, but validity and reproducibility of microarray data is a subject of ongoing scientific debate. Here we demonstrate how combining genetic and gene expression data provide a basis for biologically relevant assessment of the current state of microarray technology. We profile liver samples from a murine F2 intercross population using Affymetrix microarrays.

ORGANISM(S): Mus musculus

PROVIDER: GSE20902 | GEO | 2011/02/02

SECONDARY ACCESSION(S): PRJNA129653

REPOSITORIES: GEO

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