Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Skeletal muscle and plasma microRNA profiling among patients with gastrointestinal cancer

ABSTRACT: We profiled microRNAs and other small non-coding RNAs in skeletal muscle and plasma samples obtained from gastrointestinal cancer patients and controls and evaluated the association of differentially expressed small non-coding RNAs with the level of muscularity.

ORGANISM(S): Homo sapiens

PROVIDER: GSE210546 | GEO | 2024/01/03

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Skeletal muscle and plasma microRNA profiling among patients with gastrointestinal cancer

Project description:Skeletal muscle and plasma microRNA profiling among patients with gastrointestinal cancer

| PRJNA866134 | ENA

Circulating miRNAs spectra in plasma of multiple myeloma patients compared with healthy individuals

Project description:MicroRNAs (miRNAs) are a class of small non-coding single-stranded RNAs whose dysregulation of expression plays an important role in cancer development. Circulating miRNAs are novel biomarkers in several cancers. Thus, we explored whether the miRNAs in plasma could be useful clinical biomarkers for multiple myeloma (MM) patients. The expression levels of four miRNAs in plasma were upregulated while eight miRNAs were downregulated in MM patients compared with healthy controls according to microarray. MiRNA microarray was conducted to determine deregulated miRNAs in plasma of 9 MM patients and 7 healthy controls.

2014-01-16 | E-GEOD-54156 | biostudies-arrayexpress

Circulating miRNAs spectra in plasma of multiple myeloma patients compared with healthy individuals

2014-01-16 | GSE54156 | GEO

Solea senegalensis

Project description:Small non-coding RNAs isolated from Solea senegalensis blood plasma sequencing

| PRJNA438434 | ENA

Plasma Multi-omics Nucleic Acid Landscape of Gastrointestinal Cancer

Project description:Plasma Multi-omics Nucleic Acid Landscape of Gastrointestinal Cancer

| PRJNA774782 | ENA

Plasma microRNA signatures for perioperative myocardial injury.

Project description:The pathophysiological mechanism(s) underlying PMI remain controversial. Small non-coding molecules that modulate gene expression may enhance the detection of myocardial injury and provide further mechanistic insight. We profiled plasma exosomal microRNA in patients who sustained PMI after elective non-cardiac surgery

2020-07-26 | GSE144777 | GEO

miRNA expression data from skeletal muscle stem cells

Project description:It has been shown recently that non-coding RNAs including miRNAs are involved in the development of skeletal muscle progenitors and to maintain the quiescent condition of adult skeletal muscle stem cells. To identify the difference among developing skeletal muscle-committed progenitors or stem cells detected by Pax3-GFP; MyoD-primed RFP expressions, miRNA microarray was performed.

2014-08-01 | GSE48412 | GEO

RNA seq from plasma exosome before and after chemoradiotherapy for cervical cancer patients

Project description:We sequenced plasma exosomal RNA obtained from 58 blood samples from 29 cervical cancer patients treated with concurrent chemoradiotherapy (CCRT) followed by intracavitary brachytherapy. The patients with 2018 International Federation of Gynecology and Obstetrics [FIGO] stage IB-IVB at diagnosis were included. The 29 cervical cancer patients had two blood samples for each patient drawn before and after CCRT. Next generation sequencing data from plasma exosome included small RNAs, long non-coding RNAs, and mRNAs, of which miRNAs and mRNAs were used for analysis. The log2 fold change values were calculated between the two samples from each patient to detect miRNAs as predictors of early progression and metastasis. We analysed their biological functions through miRNA-mRNA network analysis after selecting several potential exosomal miRNAs associated with clinical results.

2021-05-23 | E-MTAB-10215 | biostudies-arrayexpress

Circulating miRNAs. isomiRs and small RNA clusters in human plasma and breast milk

Project description:Circulating small RNAs. including miRNAs but also isomiRs and other RNA species. have the potential to be used as non-invasive biomarkers for communicable and non-communicable diseases. This study aims to characterize miRNAs. isomiRs and small RNA clusters in biofluids. to compare their profiles. and to help in the establishment of standard guidelines. For this purpose. RNA from plasma and breast milk samples from 15 healthy postpartum mothers was extracted. Small RNA libraries were prepared with the NEBNext® small RNA library preparation kit and sequenced in an Illumina HiSeq2000 platform. After an initial quality control. miRNAs. isomiRs and clusters of small RNAs were annotated using seqBuster/seqCluster framework. The average amount of extracted RNA was 81 ng/mL [standard deviation (SD): 41] and 3985 ng/mL (SD: 3767) for plasma and breast milk. respectively. Mean number of good quality reads was 4.04 million (M) (40.01% of the reads) in plasma and 12.5M (89.6%) in breast milk. One thousand one hundred eighty two miRNAs. 74.317 isomiRs and 1.053 small RNA clusters that included piwi-interfering RNAs (piRNAs). tRNAs. small nucleolar RNAs (snoRNA) and small nuclear RNAs (snRNAs) were detected. Samples grouped by biofluid. with 308 miRNAs. 4.737 isomiRs and 778 small RNA clusters differentially detected. In summary. plasma and milk showed a completely different small RNA profile. In both. miRNAs. piRNAs. tRNAs. snRNAs. and snoRNAs were identified. confirming the presence of non-miRNA species in biofluids

2018-03-14 | GSE107524 | GEO

Subcellular localization analysis of long non-non coding RNAs (lncRNAs) in skeletal muscle myofibers

Project description:Subcellular localization analysis of long non-non coding RNAs (lncRNAs) in skeletal muscle myofibers

| PRJNA448919 | ENA