Effect of depletion of SOD1 on gene expression of organoid culture

ABSTRACT: To investigate the function of SOD1 in regulation of ISC growth, we established intestinal organoids from tamoxifen–inducible intestinal epithelial cell (IEC)–specific Sod1 knockout (Sod1f/f; Vil-creERT2) mice. We then performed gene expression profiling analysis using data obtained from RNA-seq of Sod1f/f and Sod1f/f;Vil-creERT2 organoids after 3 days of tamoxifen treatment. Organoids were derived from three mice of each genotype.

ORGANISM(S): Mus musculus

PROVIDER: GSE211035 | GEO | 2022/08/12

REPOSITORIES: GEO